Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413851 | 0.85 | RAB9A (0.62) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL17788443 | 0.85 | HIF1A (0.68) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL2115530 | 0.84 | RAB9A (0.61) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL17788518 | 0.80 | SCD (0.55) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL13363887 | 0.80 | TP53 (0.59) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL7424477 | 0.79 | L3MBTL1 (0.52) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL30046162 | 0.79 | L3MBTL1 (0.52) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL31039788 | 0.79 | ALDH1A1 (0.70) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL369290 | 0.79 | ALDH1A1 (0.70) | RAB9AKMT2ASMN1; SMN2TP53NPC1 | |
| SCHEMBL946826 | 0.78 | MKNK1 (0.50) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856735-B1 | FUSED BICYCLIC HETEROCYCLES AS THERAPEUTIC AGENTS | UNIV NEW YORK (US) | 2023-09-06 | — | — | EP | disclosed |