SCHEMBL26258333

SCHEMBL26258333

C1=Cc2c(n(-c3ccccc3-c3ccc(-c4ccccc4)cc3)c3ccc4c(c5ccccc5n4-c4ccccc4)c23)CC1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ KMT2A Q03164 2/20 0.30
▸ IL1R1 P14778 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26012104 0.94 KDM4E (0.31) L3MBTL1KDM4EATM
SCHEMBL26018299 0.92 KDM4E (0.30) L3MBTL1KDM4EATM
SCHEMBL26795725 0.90 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL25802283 0.89 L3MBTL1 (0.38) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL26371892 0.86 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL25616786 0.86 L3MBTL1 (0.37) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL26481780 0.85 MGLL (0.36) L3MBTL1KDM4EATMALDH1A1
SCHEMBL25616919 0.85 ATM (0.36) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL25829189 0.84 KDM4E (0.35) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL26294757 0.83 MAPK14 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 L3MBTL1 1106/4885KDM4E 3655/4885ATM 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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