SCHEMBL26259487

SCHEMBL26259487

COc1ccc2c(C#N)c(OC)cc(C#N)c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HTT P42858 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
PABPC1 P11940 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP3 P42574 1/20 0.43
NCOA1 Q15788 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
AR P10275 3/20 0.42
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
CLK1 P49759 4/20 0.41
CDK5 Q00535 4/20 0.41
DYRK1A Q13627 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26259459 0.81 IMPDH2 (0.61) KDM4EMAPTARPOLBGAA
SCHEMBL26259323 0.75 NQO1 (0.49) KDM4EMEN1KMT2AHTTLMNA
SCHEMBL26259630 0.74 MAPT (0.48) KDM4EMEN1KMT2AHTTLMNA
SCHEMBL26259612 0.73 IMPDH2 (0.64) KDM4ELMNAMAPTARPOLB
SCHEMBL1608900 0.73 AR (0.69) KDM4EARPOLBGAAALDH1A1
SCHEMBL1762094 0.73 ALDH1A1 (0.63) KDM4EMEN1KMT2AMAPTAR
SCHEMBL30730992 0.73 ALDH1A1 (0.63) KDM4EMEN1KMT2AMAPTAR
SCHEMBL26261571 0.73 CA12 (0.36) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL26259481 0.73 ATM (0.39) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL26259480 0.73 CA12 (0.36) KDM4EMEN1KMT2AMAPTCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND NUDC, CCNL2, SPIN3 KDM4E 1663/4885MEN1 379/4885KMT2A 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.