SCHEMBL26263201

SCHEMBL26263201

CC[C@H](NC(=O)c1ccc(-c2ccc(F)cc2)o1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 9/20 0.60
ALDH1A1 P00352 5/20 0.56
KDM4E B2RXH2 4/20 0.56
LMNA P02545 2/20 0.56
HPGD P15428 1/20 0.56
PTPN1 P18031 1/20 0.51
C3AR1 Q16581 3/20 0.50
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
SI P14410 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26263209 0.89 SUCNR1 (0.61) SUCNR1ALDH1A1HPGDC3AR1
SCHEMBL26263232 0.88 SUCNR1 (0.61) SUCNR1C3AR1
SCHEMBL26263219 0.88 SUCNR1 (0.61) SUCNR1ALDH1A1KDM4EHPGDC3AR1
SCHEMBL26264257 0.87 SUCNR1 (0.69) SUCNR1ALDH1A1KDM4ELMNAHPGD
SCHEMBL26263245 0.86 SUCNR1 (0.56) SUCNR1KDM4E
SCHEMBL26263243 0.86 SUCNR1 (0.68) SUCNR1ALDH1A1C3AR1MEN1MGAM
SCHEMBL26263246 0.84 SUCNR1 (0.59) SUCNR1C3AR1
SCHEMBL26263253 0.84 SUCNR1 (0.83) SUCNR1C3AR1NPC1
SCHEMBL26263250 0.83 SUCNR1 (0.62) SUCNR1KDM4EMAPT
SCHEMBL26263255 0.83 SUCNR1 (0.64) SUCNR1C3AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION UNIV NEW YORK (US) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION SUCNR1, SYNGR2, TSPO SUCNR1 1/4885ALDH1A1 1666/4885KDM4E 3613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.