SCHEMBL26263246

SCHEMBL26263246

CC[C@H](NC(=O)c1ccc(-c2ccc(C#N)cc2)o1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 12/20 0.59
C3AR1 Q16581 2/20 0.55
KCNH2 Q12809 1/20 0.52
SCN10A Q9Y5Y9 1/20 0.52
ICMT O60725 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26264366 0.88 SUCNR1 (0.69) SUCNR1C3AR1KCNH2SCN10A
SCHEMBL26263209 0.86 SUCNR1 (0.61) SUCNR1C3AR1
SCHEMBL26263219 0.85 SUCNR1 (0.61) SUCNR1C3AR1ICMT
SCHEMBL26263232 0.85 SUCNR1 (0.61) SUCNR1C3AR1ICMT
SCHEMBL26263201 0.84 SUCNR1 (0.60) SUCNR1C3AR1
SCHEMBL26263253 0.83 SUCNR1 (0.83) SUCNR1C3AR1ICMT
SCHEMBL26263243 0.83 SUCNR1 (0.68) SUCNR1C3AR1ICMT
SCHEMBL23091269 0.82 KCNH2 (0.58) SUCNR1C3AR1KCNH2SCN10A
SCHEMBL26263245 0.81 SUCNR1 (0.56) SUCNR1
SCHEMBL26263255 0.80 SUCNR1 (0.64) SUCNR1C3AR1ICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION UNIV NEW YORK (US) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION SUCNR1, SYNGR2, TSPO SUCNR1 1/4885C3AR1 3636/4885KCNH2 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.