SCHEMBL26263243

SCHEMBL26263243

CC[C@H](NC(=O)c1ccc(-c2ccc(OC)cc2)o1)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 12/20 0.68
ICMT O60725 1/20 0.58
C3AR1 Q16581 1/20 0.53
MMP13 P45452 1/20 0.53
PIN1 Q13526 1/20 0.53
MGAM O43451 1/20 0.49
GAA P10253 1/20 0.49
SI P14410 1/20 0.49
MGAM2 Q2M2H8 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
POLB P06746 1/20 0.49
MAPT P10636 1/20 0.49
THRB P10828 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26263253 0.90 SUCNR1 (0.83) SUCNR1ICMTC3AR1
SCHEMBL26263255 0.89 SUCNR1 (0.64) SUCNR1ICMTC3AR1MMP13
SCHEMBL26264363 0.89 SUCNR1 (0.81) SUCNR1ICMTC3AR1MMP13PIN1
SCHEMBL26263209 0.88 SUCNR1 (0.61) SUCNR1C3AR1ALDH1A1
SCHEMBL26263250 0.87 SUCNR1 (0.62) SUCNR1ICMTMAPT
SCHEMBL26263219 0.87 SUCNR1 (0.61) SUCNR1ICMTC3AR1MMP13MGAM
SCHEMBL26263232 0.87 SUCNR1 (0.61) SUCNR1ICMTC3AR1
SCHEMBL26263201 0.86 SUCNR1 (0.60) SUCNR1C3AR1MGAMGAASI
SCHEMBL12071407 0.83 SUCNR1 (0.57) SUCNR1ICMTC3AR1MMP13PIN1
SCHEMBL26263246 0.83 SUCNR1 (0.59) SUCNR1ICMTC3AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION UNIV NEW YORK (US) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION SUCNR1, SYNGR2, TSPO SUCNR1 1/4885ICMT 4568/4885C3AR1 3636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.