Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627023 | 0.88 | CYP11B2 (0.54) | CYP11B2CYP11B1CYP19A1NISCHPTGS2 | |
| SCHEMBL13333729 | 0.85 | CYP19A1 (0.34) | CYP11B2CYP11B1CYP19A1NISCHESR1 | |
| SCHEMBL3414856 | 0.85 | CYP11B2 (0.51) | CYP11B2CYP11B1CYP19A1NISCHPTGS2 | |
| SCHEMBL13353173 | 0.84 | CYP19A1 (0.34) | CYP11B2CYP11B1CYP19A1NISCHPTGS2 | |
| SCHEMBL22929182 | 0.82 | CYP19A1 (0.33) | CYP11B2CYP11B1CYP19A1NISCH | |
| SCHEMBL13710934 | 0.82 | CYP19A1 (0.33) | CYP11B2CYP11B1CYP19A1NISCH | |
| SCHEMBL13333504 | 0.82 | HTT (0.33) | CYP11B2CYP11B1CYP19A1NISCHHTT | |
| SCHEMBL25736312 | 0.82 | CYP11B1 (0.41) | CYP11B2CYP11B1CYP19A1NISCHPTGS2 | |
| SCHEMBL21698363 | 0.81 | CYP19A1 (0.36) | CYP11B2CYP11B1CYP19A1NISCHESR1 | |
| SCHEMBL2627005 | 0.81 | CYP11B1 (0.34) | CYP11B2CYP11B1NISCHL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8164251-B2 | Aromatic amine derivatives and organic electroluminescence devices using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8164251-B2 | Aromatic amine derivatives and organic electroluminescence devices using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090085468-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20090085468-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090085468-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME | TYR, EML4, MAOA | CYP11B2 2449/4885CYP11B1 2926/4885CYP19A1 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.