Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2626975 | 0.87 | CYP11B1 (0.43) | CYP11B1CYP11B2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2627026 | 0.86 | CYP11B1 (0.46) | CYP11B1CYP11B2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL12128418 | 0.84 | RELA (0.35) | CYP11B1CYP11B2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2627027 | 0.83 | CYP11B1 (0.38) | CYP11B1CYP11B2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2626997 | 0.83 | CYP11B1 (0.33) | CYP11B1CYP11B2IP6K1IP6K3 | |
| SCHEMBL25736312 | 0.82 | CYP11B1 (0.41) | CYP11B1CYP11B2ALDH1A1KDM4EMAPT | |
| SCHEMBL2626987 | 0.81 | CYP11B2 (0.44) | CYP11B1CYP11B2L3MBTL1NISCH | |
| SCHEMBL2627001 | 0.77 | APP (0.38) | CYP11B1CYP11B2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14111991 | 0.77 | ESR1 (0.35) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14111989 | 0.77 | ESR1 (0.35) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8164251-B2 | Aromatic amine derivatives and organic electroluminescence devices using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8164251-B2 | Aromatic amine derivatives and organic electroluminescence devices using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090085468-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20090085468-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090085468-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME | TYR, EML4, MAOA | CYP11B1 2926/4885CYP11B2 2449/4885ALDH1A1 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.