Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5089766 | 0.94 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL19361388 | 0.84 | BCL2L1 (0.36) | ESR1 | |
| SCHEMBL20527904 | 0.82 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL17212291 | 0.81 | HSD17B10 (0.36) | — | |
| SCHEMBL6232707 | 0.80 | ESR1 (0.34) | ESR1 | |
| SCHEMBL5688195 | 0.80 | CA2 (0.35) | ESR1 | |
| SCHEMBL5087788 | 0.80 | SMN1; SMN2 (0.38) | ESR1 | |
| SCHEMBL5091528 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL6232782 | 0.78 | LIMK1 (0.36) | — | |
| SCHEMBL29492999 | 0.78 | GPR3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-04-26 | — | — | US | disclosed |
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-04-26 | — | — | US | disclosed |
| US-7416682-B2 | Photochromic liquid crystals | CHI MEI OPTOELECTRONICS CORPORATION (TW) | 2008-08-26 | — | — | US | disclosed |
| EP-1517977-B1 | PHOTOCHROMIC LIQUID CRYSTALS | QINETIQ LTD (GB) | 2006-10-11 | — | — | EP | disclosed |
| US-20050258396-A1 | Potochromic liquid crystals | QINETIQ LIMITED (GB) | 2005-11-24 | — | — | US | disclosed |
| EP-1517977-A1 | PHOTOCHROMIC LIQUID CRYSTALS | Qinetiq Limited (GB) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004003107-A1 | POTOCHROMIC LIQUID CRYSTALS | QINETIQ LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | ABCC1, DHFR, GFPT1 | ESR1 4776/4885ESR2 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.