SCHEMBL2628205

SCHEMBL2628205

O=C(O)Cc1cn(C[18F])nn1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.37
HDAC1 Q13547 4/20 0.37
FOLH1 Q04609 2/20 0.36
HSP90AB1 P08238 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALOX5 P09917 1/20 0.35
HRH4 Q9H3N8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19296374 0.80 CYP1A2 (0.39) HDAC1FOLH1
SCHEMBL18623460 0.79 L3MBTL1 (0.44) L3MBTL1HRH4HRH3
SCHEMBL25836729 0.79 SRC (0.38) FABP4HSP90AB1L3MBTL1
SCHEMBL24665771 0.76 CYP19A1 (0.60) HDAC1HSP90AB1HRH4
SCHEMBL22059619 0.75 NR1H4 (0.44) FABP4HDAC1FOLH1HRH4HRH3
SCHEMBL22060200 0.75 NAMPT (0.42) FOLH1HRH4HRH3
SCHEMBL2628207 0.74 CYP4F2 (0.40) FOLH1HSP90AB1ALOX5
SCHEMBL18605543 0.74 CYP4F2 (0.40) FOLH1HSP90AB1ALOX5
SCHEMBL9914065 0.73 BRD4 (0.39) FABP4L3MBTL1
SCHEMBL15803295 0.73 HDAC1 (0.58) HDAC1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120100073-A1 PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE WASHINGTON UNIVERSITY (US) 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120100073-A1 PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE LIPC, PNLIP, FFAR1 FABP4 5/4885HDAC1 3094/4885FOLH1 488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.