SCHEMBL2628207

SCHEMBL2628207

O=C(O)Cn1cc(C[18F])nn1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
HSP90AB1 P08238 2/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
ALOX5 P09917 1/20 0.38
FOLH1 Q04609 3/20 0.37
GUSB P08236 2/20 0.37
HTT P42858 1/20 0.37
SRC P12931 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18605543 1.00 CYP4F2 (0.40) CYP4F2CYP4A11HSP90AB1POLBKMT2A
SCHEMBL28759020 0.83 CYP4F2 (0.43) CYP4F2CYP4A11HSP90AB1POLBKMT2A
SCHEMBL3730288 0.83 NOTUM (0.49) CYP4F2CYP4A11POLBKMT2AHTT
SCHEMBL274593 0.83 FOLH1 (0.52) CYP4F2CYP4A11FOLH1
SCHEMBL4675850 0.81 CYP4F2 (0.43) CYP4F2CYP4A11HSP90AB1POLBKMT2A
SCHEMBL2628186 0.81 CYP4F2 (0.40) CYP4F2CYP4A11HSP90AB1POLBKMT2A
SCHEMBL21063617 0.81 MAOA (0.47) CYP4F2CYP4A11POLBKMT2AHTT
SCHEMBL15199191 0.81 MAOB (0.43) CYP4F2CYP4A11HSP90AB1POLBKMT2A
SCHEMBL23038420 0.80 POLB (0.57) CYP4F2CYP4A11POLBKMT2A
SCHEMBL19296368 0.80 LOXL2 (0.37) POLBKMT2AFOLH1GUSBSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120100073-A1 PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE WASHINGTON UNIVERSITY (US) 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120100073-A1 PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE LIPC, PNLIP, FFAR1 CYP4F2 341/4885CYP4A11 1438/4885HSP90AB1 1001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.