Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26291617 | 0.91 | THRB (0.40) | APPCYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL26291627 | 0.86 | APP (0.37) | APPCYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL26291461 | 0.86 | RAB9A (0.40) | RAB9AALDH1A1NPC1KDM4EGLA | |
| SCHEMBL22245815 | 0.83 | S1PR1 (0.35) | APPCYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL26291695 | 0.82 | ALDH1A1 (0.40) | APPCYP1A2RAB9AALDH1A1NPC1 | |
| SCHEMBL25896587 | 0.80 | CYP1A2 (0.33) | APPCYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL26291620 | 0.78 | S1PR1 (0.39) | APPCYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL26291480 | 0.77 | PTPN1 (0.47) | APPCYP2C19RAB9AALDH1A1NPC1 | |
| SCHEMBL26291477 | 0.77 | PTPN1 (0.47) | APPCYP2C19RAB9AALDH1A1NPC1 | |
| SCHEMBL26291539 | 0.77 | PTPN1 (0.58) | APPCYP2C19RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | APP 899/4885CYP1A2 1796/4885CYP2E1 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.