Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PON1 | P27169 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26293022 | 0.86 | MAPT (0.42) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL31362933 | 0.85 | AHR (0.56) | ESR1ESR2GAAKDM4EPON1 | |
| SCHEMBL17920843 | 0.82 | MAOA (0.44) | ESR1ESR2MAOBALDH1A1HPGD | |
| SCHEMBL11711426 | 0.82 | CYP1A2 (0.47) | ESR1ESR2MAOBALDH1A1HPGD | |
| SCHEMBL9927267 | 0.80 | MAOB (0.53) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL21315938 | 0.80 | MAOB (0.39) | ESR1ESR2MAOBALDH1A1HPGD | |
| SCHEMBL12433585 | 0.78 | MAOA (0.41) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL20156784 | 0.78 | MAOB (0.44) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL15195120 | 0.76 | MAOB (0.50) | MAOBALDH1A1HPGDGAAKDM4E | |
| SCHEMBL862364 | 0.75 | MAOB (0.46) | MAOBALDH1A1HPGDGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234937-A1 | INDENOAZANAPHTHALENES | MERCK PATENT GMBH (DE) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234937-A1 | INDENOAZANAPHTHALENES | NQO1, CYP2D6, SQOR | ESR1 205/4885ESR2 712/4885MAOB 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.