Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PON1 | P27169 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26293017 | 0.86 | ESR1 (0.49) | MAPTKDM4EMAPK1KMT2AESR1 | |
| SCHEMBL21280631 | 0.81 | MAPT (0.40) | MAPTKDM4EMAPK1CYP3A4KMT2A | |
| SCHEMBL17920843 | 0.81 | MAOA (0.44) | MAPTKDM4EMAPK1CYP3A4KMT2A | |
| SCHEMBL17166806 | 0.81 | CYP1A2 (0.47) | MAPTKDM4EMAPK1CYP3A4KMT2A | |
| SCHEMBL11992359 | 0.79 | MAPT (0.41) | MAPTKDM4EMAPK1CYP3A4KMT2A | |
| SCHEMBL1610145 | 0.79 | MAPT (0.50) | MAPTKDM4EMAPK1CYP3A4KMT2A | |
| SCHEMBL15725991 | 0.77 | KDM4E (0.43) | MAPTKDM4EMAPK1CYP3A4KMT2A | |
| SCHEMBL18327949 | 0.76 | ALDH1A1 (0.46) | MAPTKDM4EMAPK1CYP3A4KMT2A | |
| SCHEMBL10141873 | 0.75 | MAOB (0.47) | MAPTKDM4EMAPK1CYP3A4KMT2A | |
| SCHEMBL19155599 | 0.74 | MAPT (0.47) | MAPTKDM4EMAPK1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234937-A1 | INDENOAZANAPHTHALENES | MERCK PATENT GMBH (DE) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234937-A1 | INDENOAZANAPHTHALENES | NQO1, CYP2D6, SQOR | MAPT 2276/4885KDM4E 1585/4885MAPK1 4089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.