SCHEMBL262950

SCHEMBL262950

CC(SC(=S)c1ccccc1)(C(=O)O)N1C(=O)CCC1=O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.34
EPHX1 P07099 1/20 0.34
RAB9A P51151 4/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 3/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
NPC1 O15118 3/20 0.32
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822806 0.73 EPHX1 (0.42) KMT2AEPHX1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL43721 0.72 POLB (0.32) POLB
SCHEMBL9285475 0.72 POLB (0.32) POLB
SCHEMBL17640335 0.70 MGLL (0.37) KMT2ARAB9ASMN1; SMN2ALDH1A1MAPK1
SCHEMBL21382782 0.69 EPHX1 (0.39) KMT2AEPHX1SMN1; SMN2ALDH1A1MAPT
SCHEMBL8350896 0.69 KMT2A (0.36) KMT2ARAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL236901 0.69 ALDH1A1 (0.41) KMT2AEPHX1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13377791 0.68 EPHX1 (0.41) KMT2AEPHX1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL21749922 0.68 HDAC3 (0.41) KMT2AEPHX1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL3469006 0.68 EHMT2 (0.40) KMT2ARAB9ASMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007003782-A2 NOVEL FUNCTIONALISED TRANSFER AGENTS FOR CONTROLLED RADICAL POLYMERISATION RAFT, RAFT METHODS USING SAID TRANSFER AGENTS AND POLYMERS OBTAINABLE THEREBY BIOMERIEUX S.A. (FR) 2007-01-11 WO claimed
US-8133411-B2 Fluorescent polymers soluble in an aqueous solution and a method for the production thereof BIOMERIEUX S.A. (FR) 2012-03-13 US disclosed
US-20080290321-A1 Fluorescent Polymers Soluble in an Aqueous Solution and a Method for the Production Thereof BIOMERIEUX S.A. (FR) 2008-11-27 US disclosed
EP-1899434-A1 FLUORESCENT POLYMERS SOLUBLE IN AN AQUEOUS SOLUTION AND A METHOD FOR THE PRODUCTION THEREOF bioMérieux S.A. (FR) 2008-03-19 EP disclosed
WO-2007003781-A1 FLUORESCENT POLYMERS SOLUBLE IN AN AQUEOUS SOLUTION AND A METHOD FOR THE PRODUCTION THEREOF BIOMERIEUX S.A. (FR) 2007-01-11 WO disclosed
WO-2007003782-A2 NOVEL FUNCTIONALISED TRANSFER AGENTS FOR CONTROLLED RADICAL POLYMERISATION RAFT, RAFT METHODS USING SAID TRANSFER AGENTS AND POLYMERS OBTAINABLE THEREBY BIOMERIEUX S.A. (FR) 2007-01-11 WO disclosed