SCHEMBL26297617

SCHEMBL26297617

Cc1c(-c2ccccc2)c2c(c3ccccc3n2C)n1C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ ALKBH5 Q6P6C2 1/20 0.47
▸ FTO Q9C0B1 1/20 0.47
▸ KDM4E B2RXH2 5/20 0.46
▸ HSD17B10 Q99714 5/20 0.46
▸ ALDH1A1 P00352 5/20 0.46
▸ HPGD P15428 4/20 0.46
▸ GLA P06280 2/20 0.46
▸ GAA P10253 2/20 0.46
▸ MAPT P10636 2/20 0.46
▸ GPR3 P46089 1/20 0.45
▸ NPSR1 Q6W5P4 2/20 0.42
▸ CYP2C19 P33261 2/20 0.41
▸ MAOB P27338 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26168251 0.85 LMNA (0.44) LMNAKMT2ASMN1; SMN2ALKBH5FTO
SCHEMBL29634190 0.83 KMT2A (0.54) LMNAKMT2ASMN1; SMN2ALKBH5FTO
SCHEMBL26168119 0.83 KMT2A (0.54) LMNAKMT2ASMN1; SMN2ALKBH5FTO
SCHEMBL16376455 0.79 GPR3 (0.70) LMNAKMT2AALKBH5FTOKDM4E
SCHEMBL26297612 0.78 ALKBH5 (0.53) LMNAKMT2AALKBH5FTOKDM4E
SCHEMBL19233713 0.75 ALKBH5 (0.50) LMNAKMT2AALKBH5FTOKDM4E
SCHEMBL26168131 0.75 LMNA (0.46) LMNAKMT2ASMN1; SMN2ALKBH5FTO
SCHEMBL9959682 0.73 KDM4E (0.51) LMNAKMT2ASMN1; SMN2ALKBH5FTO
SCHEMBL9955515 0.73 KDM4E (0.51) LMNAKMT2ASMN1; SMN2ALKBH5FTO
SCHEMBL18701256 0.72 MAPT (0.45) LMNAKMT2ASMN1; SMN2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, PORCN LMNA 2148/4885KMT2A 4003/4885SMN1; SMN2 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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