Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223413 | 0.81 | GAA (0.49) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| SCHEMBL358889 | 0.81 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| SCHEMBL193631 | 0.79 | LMNA (0.50) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| SCHEMBL352276 | 0.79 | GAA (0.53) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| SCHEMBL3643406 | 0.79 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| Hydrochloric Acid SCHEMBL19119186 | 0.79 | GAA (0.47) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| SCHEMBL2176508 | 0.77 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| Hydrochloric Acid SCHEMBL5009791 | 0.77 | GAA (0.51) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| SCHEMBL8571245 | 0.76 | GFER (0.47) | ALDH1A1L3MBTL1LMNAGAAALOX15 | |
| SCHEMBL14676577 | 0.76 | HPGD (0.56) | ALDH1A1L3MBTL1ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254416-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2016-09-07 | — | — | EP | disclosed |
| US-8987455-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2015-03-24 | — | — | US | disclosed |
| US-8653078-B2 | Herbicidal pyrido[2,3-b]pyrazines | SYNGENTA LIMITED | 2014-02-18 | — | — | US | disclosed |
| US-8557840-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-10-15 | — | — | US | disclosed |
| US-20130137574-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-05-30 | — | — | US | disclosed |
| US-8338598-B2 | Herbicidal pyrido[2,3-B]pyrazines and their use as herbicides | SYNGENTA LIMITED | 2012-12-25 | — | — | US | disclosed |
| EP-2057154-B1 | PYRIDO [2, 3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2012-11-14 | — | — | EP | disclosed |
| US-8217055-B2 | Pyrido-pyrazine derivatives useful as herbicidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-10 | — | — | US | disclosed |
| US-8133847-B2 | Pyrido[2,3-B]pyrazine derivatives useful as herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20110034334-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-10 | — | — | US | disclosed |
| US-20110021351-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2254417-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| EP-2254416-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| EP-2102205-B1 | PYRIDO-PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2010-09-01 | — | — | EP | disclosed |
| US-20100167929-A1 | PYRIDO-PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20090305892-A1 | PYRIDO[2,3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-12-10 | — | — | US | disclosed |
| WO-2009090402-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
| WO-2009090401-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
| EP-2057154-A1 | PYRIDO [2, 3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008009908-A1 | PYRIDO [2, 3-B] PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137574-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, CBR1 | ALDH1A1 133/4885L3MBTL1 3016/4885LMNA 3807/4885 |
| US-20100167929-A1 | PYRIDO-PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | CBR3, PNPO, CBR1 | ALDH1A1 354/4885L3MBTL1 2960/4885LMNA 3893/4885 |
| US-20110021351-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, TH | ALDH1A1 299/4885L3MBTL1 3091/4885LMNA 3883/4885 |
| US-20110034334-A1 | HERBICIDAL COMPOUNDS | CYP4Z1, CYP4F3, DDT | ALDH1A1 119/4885L3MBTL1 2349/4885LMNA 2904/4885 |
| US-20090305892-A1 | PYRIDO[2,3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | PNPO, CBR3, CBR1 | ALDH1A1 286/4885L3MBTL1 1707/4885LMNA 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.