Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26310974 | 0.83 | PARP1 (0.53) | PARP1USP2GAAL3MBTL1MAPK1 | |
| SCHEMBL26311050 | 0.83 | L3MBTL1 (0.53) | PARP1USP2GAAL3MBTL1MAPK1 | |
| SCHEMBL26654694 | 0.81 | HSD17B10 (0.54) | PARP1USP2GAAL3MBTL1MAPK1 | |
| SCHEMBL23571859 | 0.79 | USP2 (0.65) | USP2GAAHSD17B10TP53TSHR | |
| SCHEMBL29823082 | 0.79 | USP2 (0.65) | USP2GAAHSD17B10TP53TSHR | |
| SCHEMBL11831795 | 0.77 | HSD17B10 (0.61) | PARP1USP2GAAL3MBTL1MAPK1 | |
| SCHEMBL23534259 | 0.77 | L3MBTL1 (0.49) | PARP1USP2GAAL3MBTL1MAPK1 | |
| SCHEMBL7003159 | 0.77 | PARP1 (0.74) | PARP1USP2GAAL3MBTL1MAPK1 | |
| SCHEMBL18581866 | 0.76 | USP2 (0.56) | USP2GAAL3MBTL1HSD17B10TP53 | |
| SCHEMBL29498308 | 0.76 | MAOB (0.49) | PARP1MAPK1HSD17B10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178035-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-09-21 | — | — | WO | disclosed |