Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.48 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.48 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.48 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.48 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308195 | 0.83 | SENP3 (0.62) | TDP1TSHRALDH1A1HSD17B10SENP3 | |
| SCHEMBL3308193 | 0.83 | SENP3 (0.62) | TDP1TSHRALDH1A1HSD17B10SENP3 | |
| SCHEMBL3876794 | 0.82 | TSHR (0.53) | TDP1TSHRALDH1A1HSD17B10SENP3 | |
| SCHEMBL7050591 | 0.80 | TSHR (0.52) | TDP1TSHRALDH1A1HSD17B10SENP3 | |
| SCHEMBL9514970 | 0.80 | TDP1 (0.52) | TDP1TSHRALDH1A1HSD17B10SENP3 | |
| SCHEMBL8727724 | 0.80 | NOS1 (0.40) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL8915272 | 0.80 | TDP1 (0.52) | TDP1TSHRALDH1A1HSD17B10SENP3 | |
| SCHEMBL8916268 | 0.80 | TDP1 (0.52) | TDP1TSHRALDH1A1HSD17B10SENP3 | |
| SCHEMBL10800723 | 0.78 | POLB (0.69) | TDP1TSHRALDH1A1HSD17B10SENP3 | |
| SCHEMBL10800727 | 0.78 | POLB (0.69) | TDP1TSHRALDH1A1HSD17B10SENP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348344-B1 | Azo dyes | CIBA GEIGY AG (CH) | 1993-12-29 | — | — | EP | claimed |
| US-RE29585-E | DYEING WOOL | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | claimed |
| US-3956263-A | 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs | CIBA-GEIGY AG (CH) | 1976-05-11 | — | — | US | claimed |
| US-8802829-B2 | Rinsable dyes and methods for their preparation | Spectra Colors Corp. (US) | 2014-08-12 | — | — | US | disclosed |
| US-8772545-B2 | Rinsable dyes and methods for their preparation | Spectra Colors Corp. (US) | 2014-07-08 | — | — | US | disclosed |
| US-8664371-B2 | Rinsable dyes and methods for their preparation | Spectra Colors Corp. (US) | 2014-03-04 | — | — | US | disclosed |
| US-8653247-B2 | Rinsable dyes and methods for their preparation | Spectra Colors Corp. (US) | 2014-02-18 | — | — | US | disclosed |
| US-20120289739-A1 | Rinsable Dyes and Methods for their Preparation | Spectra Colors Corp. | 2012-11-15 | — | — | US | disclosed |
| US-20120226030-A1 | Rinsable Dyes and Methods for their Preparation | Spectra Colors Corp. | 2012-09-06 | — | — | US | disclosed |
| WO-2012073249-A1 | A NOVEL PROCESS FOR THE PREPARATION OF 3-(BENZYLOXY)- BENZENETHIOL, A KEY INTERMEDIATE FOR THE PREPARATION OF PHARMACEUTICAL DRUGS. | ARCH PHARMALABS LIMITED (IN) | 2012-06-07 | — | — | WO | disclosed |
| US-20120101264-A1 | Rinsable dyes and methods for their preparation | Spectra Colors Corp. | 2012-04-26 | — | — | US | disclosed |
| US-20120004400-A1 | Rinsable dyes and methods for their preparation | Spectra Colors Corp. | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289739-A1 | Rinsable Dyes and Methods for their Preparation | ARSA, HNRNPUL1, ALKBH1 | TDP1 1251/4885TSHR 3499/4885ALDH1A1 196/4885 |
| US-20120226030-A1 | Rinsable Dyes and Methods for their Preparation | ARSA, HNRNPUL1, ALKBH1 | TDP1 1251/4885TSHR 3499/4885ALDH1A1 196/4885 |
| US-20120101264-A1 | Rinsable dyes and methods for their preparation | ARSA, HNRNPUL1, ALKBH1 | TDP1 1251/4885TSHR 3499/4885ALDH1A1 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.