Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 12/20 | 0.39 |
| ▸ | CA9 | Q16790 | 9/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.32 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.32 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.32 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727720 | 0.80 | CA2 (0.41) | NOS1CA2CA9CA1CA7 | |
| SCHEMBL2631143 | 0.80 | TDP1 (0.52) | NOS1CA2CA9CA1CA7 | |
| SCHEMBL10571503 | 0.78 | CA2 (0.55) | CA2CA9CA1CA7CA12 | |
| SCHEMBL6313736 | 0.77 | CA2 (0.40) | NOS1CA2CA9CA1CA7 | |
| SCHEMBL8724038 | 0.74 | F2 (0.42) | NOS1CA2CA9CA1CA7 | |
| SCHEMBL19122491 | 0.72 | CA2 (0.45) | CA2CA9CA1CA12APOBEC3G | |
| SCHEMBL8014338 | 0.72 | CA2 (0.48) | CA2CA9CA1CA12APOBEC3G | |
| SCHEMBL1889098 | 0.70 | CA12 (0.47) | CA2CA9CA1CA12 | |
| SCHEMBL1018322 | 0.68 | PGR (0.52) | LMNA | |
| SCHEMBL4619061 | 0.68 | KMT2A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | claimed |