Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569933 | 0.80 | PTGDR2 (0.45) | ALDH1A1KDM4ETDP1CCR5PTGDR2 | |
| SCHEMBL8712221 | 0.79 | PTGDR2 (0.59) | ALDH1A1KDM4ETDP1CCR5PTGDR2 | |
| SCHEMBL8712410 | 0.79 | CCR5 (0.42) | ALDH1A1KDM4ETDP1CCR5PTGDR2 | |
| SCHEMBL30152364 | 0.79 | PTGDR2 (0.59) | ALDH1A1KDM4ETDP1CCR5PTGDR2 | |
| SCHEMBL4185116 | 0.78 | SMN1; SMN2 (0.42) | ALDH1A1KDM4ECCR5PTGDR2RAB9A | |
| SCHEMBL31750611 | 0.76 | CCR5 (0.61) | ALDH1A1CCR5RAB9ALMNAHTT | |
| SCHEMBL28009643 | 0.76 | TSHR (0.41) | ALDH1A1KDM4ETDP1PTGDR2CYP3A4 | |
| SCHEMBL4014116 | 0.75 | CYP3A4 (0.42) | ALDH1A1KDM4ETDP1CCR5PTGDR2 | |
| SCHEMBL8709749 | 0.75 | CSNK2A1 (0.41) | ALDH1A1KDM4ETDP1CCR5PTGDR2 | |
| SCHEMBL578735 | 0.75 | L3MBTL1 (0.43) | KDM4ECYP3A4CYP2D6CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158631-B2 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (US) | 2012-04-17 | — | — | US | disclosed |
| US-20100330032-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | CHIN ELBERT | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100330032-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | EIF2AK2, HCCS, RTF2 | ALDH1A1 597/4885KDM4E 2295/4885TDP1 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.