Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 9/20 | 0.57 |
| ▸ | CA12 | O43570 | 8/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.57 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.57 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24162306 | 0.91 | CA9 (0.56) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL26313770 | 0.85 | CA2 (0.56) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL13508534 | 0.84 | FFAR1 (0.55) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL24162766 | 0.83 | CA2 (0.55) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL13508502 | 0.82 | LMNA (0.59) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL3690228 | 0.82 | CA9 (0.49) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL26313763 | 0.82 | CA12 (0.50) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL5046426 | 0.81 | CNR2 (0.61) | CNR2KEAP1NFE2L2 | |
| SCHEMBL9795890 | 0.81 | CA2 (0.60) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30321031 | 0.81 | CA12 (0.49) | CA9CA12CA2RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257357-A1 | PROBENECID COMPOUNDS FOR THE TREATMENT OF INFLAMMASOME-MEDIATED LUNG DISEASE | BACAINN BIOTHERAPEUTICS, LTD. (KY) | 2023-08-17 | — | — | US | disclosed |
| CN-115989219-A | Probenecid compounds for the treatment of inflammasome-mediated pulmonary diseases | 贝凯恩生物医疗技术有限公司 | 2023-04-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257357-A1 | PROBENECID COMPOUNDS FOR THE TREATMENT OF INFLAMMASOME-MEDIATED LUNG DISEASE | NLRP3, PYCARD, NLRP1 | CA9 2197/4885CA12 3513/4885CA2 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.