Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.62 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.62 |
| ▸ | CCR1 | P32246 | 2/20 | 0.61 |
| ▸ | CCR5 | P51681 | 2/20 | 0.61 |
| ▸ | CCR8 | P51685 | 2/20 | 0.61 |
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376462 | 0.80 | PSMD14 (0.67) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL2850764 | 0.78 | PSMD14 (0.65) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL6422325 | 0.77 | PSMD14 (0.62) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL5540860 | 0.77 | PSMD14 (0.62) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL11973584 | 0.77 | KDM4E (0.62) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL3718782 | 0.77 | KDM4E (0.62) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL29800848 | 0.77 | KDM4E (0.62) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL3067414 | 0.77 | PSMD14 (1.00) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL26074213 | 0.77 | KDM4E (0.62) | KDM4EPSMD14COPS5CCR1CCR5 | |
| SCHEMBL1787225 | 0.77 | KDM4E (1.00) | KDM4EPSMD14COPS5CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295108-A1 | ARYLTETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, INSECTICIDAL AGENT CONTAINING THE COMPOUND, AND METHOD OF USE THEREOF | NIHON NOHYAKU CO., LTD. (JP) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295108-A1 | ARYLTETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, INSECTICIDAL AGENT CONTAINING THE COMPOUND, AND METHOD OF USE THEREOF | TRPA1, DDT, HPD | KDM4E 773/4885PSMD14 2681/4885COPS5 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.