Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499897 | 1.00 | TRPA1 (0.57) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11499898 | 1.00 | TRPA1 (0.57) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL13461065 | 0.94 | TRPA1 (0.48) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11245383 | 0.85 | IAPP (0.39) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11245384 | 0.85 | IAPP (0.39) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11773816 | 0.82 | TRPA1 (0.52) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11773832 | 0.82 | TRPA1 (0.52) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL10808210 | 0.80 | POLB (0.70) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL30705405 | 0.80 | POLB (0.70) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL30705404 | 0.80 | POLB (0.70) | TRPA1POLBPOLA1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11738031-B2 | Compositions and methods for preventing or treating muscle conditions | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11738031-B2 | Compositions and methods for preventing or treating muscle conditions | PYGM, TNNC1, MYOF | TRPA1 1954/4885POLB 3247/4885POLA1 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.