Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272984 | 0.75 | KDM4E (0.51) | MAPTKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL19331463 | 0.71 | L3MBTL1 (0.46) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL19331371 | 0.69 | HSD17B10 (0.43) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2275127 | 0.67 | SLC9A1 (0.59) | MAPTKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL2902799 | 0.66 | L3MBTL1 (0.49) | KDM4EALDH1A1HSD17B10RXFP1L3MBTL1 | |
| SCHEMBL1004083 | 0.66 | RXFP1 (0.68) | MAPTKDM4EALDH1A1TSHRLMNA | |
| SCHEMBL2277189 | 0.65 | L3MBTL1 (0.58) | MAPTKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL9514737 | 0.65 | L3MBTL1 (0.76) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL19332523 | 0.65 | L3MBTL1 (0.48) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2905589 | 0.64 | ALDH1A1 (0.60) | KDM4EALDH1A1HSD17B10LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234552-A2 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |