Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ESRRA | P11474 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240738 | 0.87 | ALDH1A1 (0.44) | ALDH1A1ESRRAATMGAAXBP1 | |
| SCHEMBL21629685 | 0.84 | ALDH1A1 (0.41) | ALDH1A1ESRRAATMGAAXBP1 | |
| SCHEMBL4595779 | 0.84 | VCAM1 (0.47) | ALDH1A1GAALMNATYRPOLB | |
| SCHEMBL7792915 | 0.84 | FFAR1 (0.45) | ALDH1A1ESRRAATMGAAXBP1 | |
| SCHEMBL4639347 | 0.82 | GAA (0.43) | ALDH1A1ESRRAATMGAAXBP1 | |
| SCHEMBL31522502 | 0.81 | MAPT (0.41) | ALDH1A1GAAL3MBTL1ALOX15HTT | |
| SCHEMBL5454580 | 0.79 | TSHR (0.55) | GAANPSR1LMNATYR | |
| SCHEMBL13140163 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAALOX15HTTHSD17B10 | |
| SCHEMBL9359363 | 0.78 | KDM4E (0.40) | ALDH1A1ESRRAATMGAAXBP1 | |
| SCHEMBL490454 | 0.78 | MT-CO2 (0.52) | ALDH1A1ESRRAATMGAAXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997165-B1 | STABILIZER COMPOSITION FOR SILYL-MODIFIED POLYMER SEALANTS | CLARIANT INT LTD (CH) | 2023-09-06 | — | — | EP | disclosed |