SCHEMBL4595779

SCHEMBL4595779

COC(=O)CC(C)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 4/20 0.47
CA2 P00918 3/20 0.43
CA1 P00915 2/20 0.43
GAA P10253 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
PTGS1 P23219 1/20 0.42
HMGCR P04035 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GLRA3 O75311 1/20 0.39
GLRB P48167 1/20 0.39
CACNA1A O00555 1/20 0.38
CACNA2D1 P54289 1/20 0.38
CACNB1 Q02641 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8859110 0.88 VCAM1 (0.41) VCAM1CA2CA1GAAALDH1A1
SCHEMBL1070390 0.85 HMGCR (0.42) VCAM1CA2CA1GAAALDH1A1
SCHEMBL26324469 0.84 ALDH1A1 (0.46) GAAALDH1A1LMNAPOLBTYR
SCHEMBL13834991 0.83 VCAM1 (0.46) VCAM1CA2CA1GAAALDH1A1
SCHEMBL27882293 0.82 LMNA (0.39) VCAM1CA2CA1GAAALDH1A1
SCHEMBL10769690 0.82 GLRA3 (0.46) VCAM1CA2CA1GAAALDH1A1
SCHEMBL1278621 0.82 GLRA3 (0.46) VCAM1CA2CA1GAAALDH1A1
SCHEMBL11782511 0.82 VCAM1 (0.45) VCAM1CA2CA1GAAALDH1A1
SCHEMBL27882302 0.82 VCAM1 (0.48) VCAM1CA2CA1GAAALDH1A1
SCHEMBL3424148 0.81 ESR1 (0.43) VCAM1GAAHMGCRLMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2311908-B1 FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION ADEKA CORP (JP) 2017-01-04 EP disclosed
CN-104870613-A Flame retardant composition and flame-retardant synthetic resin composition ADEKA CORP 2015-08-26 CN disclosed
US-8735473-B2 Flame-retardant thermoplastic resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
CN-102066496-B Non-halogen flame-retardant synthetic resin composition ADEKA CORP 2013-10-02 CN disclosed
EP-2295500-B1 FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION ADEKA CORP (JP) 2013-01-09 EP disclosed
US-8314167-B2 Flame-retardant thermoplastic resin composition ADEKA CORPORATION (JP) 2012-11-20 US disclosed
CN-102344368-A Processing method of methyl 3,5-di-tert-butyl-4-hydroxyphenyl propionate mother solution TIANJIN SANNONGJIN TECHNOLOGY 2012-02-08 CN disclosed
CN-102066496-A Non-halogen flame-retardant synthetic resin composition ADEKA CORP 2011-05-18 CN disclosed
US-7465761-B2 Flame retardant composition with improved fluidity, flame retardant resin composition and molded products ADEKA CORPORATION (JP) 2008-12-16 US disclosed
EP-1719800-B1 FLAME RETARDANT COMPOSITION WITH ENHANCED FLUIDITY, FLAME RETARDANT RESIN COMPOSITION AND MOLDING THEREOF ADEKA CORP (JP) 2008-01-02 EP disclosed
US-20070176154-A1 Flame retardant composition with improved fluidity, flame retardant resin composition and molded products AKEKA CORPORATION (JP) 2007-08-02 US disclosed
EP-1719800-A1 FLAME RETARDANT COMPOSITION WITH ENHANCED FLUIDITY, FLAME RETARDANT RESIN COMPOSITION AND MOLDING THEREOF Asahi Denka Co., Ltd. (JP) 2006-11-08 EP disclosed