Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26324909 | 0.84 | PPARG (0.31) | PPARGPPARDPPARA | |
| SCHEMBL26324900 | 0.83 | SMN1; SMN2 (0.38) | PPARGPPARDPPARATSHR | |
| SCHEMBL26324912 | 0.83 | HDAC3 (0.32) | — | |
| SCHEMBL26324895 | 0.79 | CHRNB2 (0.37) | PPARGPPARDPPARACYP1A2CYP2C19 | |
| SCHEMBL26324897 | 0.77 | RAB9A (0.34) | PPARGPPARDPPARA | |
| SCHEMBL20565362 | 0.77 | NR1H2 (0.35) | PPARGPPARDPPARACYP1A2CYP2C19 | |
| SCHEMBL26324890 | 0.76 | ALDH1A1 (0.39) | CYP1A2CYP2C19TSHR | |
| SCHEMBL26324917 | 0.76 | HDAC1 (0.38) | TSHR | |
| SCHEMBL26324915 | 0.73 | HDAC3 (0.38) | PPARGPPARA | |
| SCHEMBL25439960 | 0.72 | HDAC3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | PPARG 4176/4885PPARD 4420/4885PPARA 3910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.