Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20564030 | 0.89 | GPR119 (0.52) | GPR119MEN1KMT2AUSP30JAK2 | |
| SCHEMBL26324875 | 0.83 | TRPM8 (0.36) | — | |
| SCHEMBL26324952 | 0.81 | GPR119 (0.40) | GPR119MEN1KMT2AUSP30MAPT | |
| SCHEMBL26324928 | 0.81 | KDM4E (0.39) | MEN1KMT2AKDM4EPKMNPC1 | |
| SCHEMBL26324931 | 0.80 | KDM4E (0.41) | MEN1KMT2AKDM4EPKMNPC1 | |
| SCHEMBL3837667 | 0.77 | MEN1 (0.61) | GPR119MEN1KMT2AUSP30JAK2 | |
| SCHEMBL2792425 | 0.76 | MEN1 (0.60) | GPR119MEN1KMT2AUSP30JAK2 | |
| SCHEMBL8333913 | 0.75 | MEN1 (0.68) | GPR119MEN1KMT2AUSP30JAK2 | |
| SCHEMBL652408 | 0.74 | MEN1 (0.57) | GPR119MEN1KMT2AUSP30JAK2 | |
| SCHEMBL7421811 | 0.74 | MEN1 (0.57) | GPR119MEN1KMT2AUSP30JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | GPR119 4808/4885MEN1 296/4885KMT2A 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.