Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.40 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20564589 | 0.91 | GPR119 (0.41) | GPR119MMP13MEN1KMT2AHRH3 | |
| SCHEMBL26324929 | 0.81 | GPR119 (0.50) | GPR119MEN1KMT2AUSP30MAPT | |
| SCHEMBL20564030 | 0.71 | GPR119 (0.52) | GPR119MEN1KMT2AUSP30MAPT | |
| SCHEMBL14637891 | 0.71 | GPR119 (0.48) | GPR119MEN1KMT2AUSP30 | |
| SCHEMBL25439897 | 0.70 | ALDH1A1 (0.59) | GPR119HRH3MAPT | |
| SCHEMBL8345392 | 0.69 | GPR119 (0.52) | GPR119 | |
| SCHEMBL31023634 | 0.68 | HDAC3 (0.44) | GPR119HRH3MAPT | |
| SCHEMBL4683070 | 0.68 | CYP2D6 (0.67) | GPR119 | |
| SCHEMBL4683076 | 0.68 | CYP2D6 (0.67) | GPR119 | |
| SCHEMBL25723347 | 0.67 | TGM2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | GPR119 4808/4885MMP13 4698/4885MEN1 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.