Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26325017 | 0.94 | KDM4E (0.34) | KDM4ETDP1L3MBTL1 | |
| SCHEMBL26325021 | 0.86 | TDP1 (0.31) | TSPOKDM4ETDP1L3MBTL1 | |
| SCHEMBL20565359 | 0.86 | TSPO (0.33) | TSPOKDM4EARTDP1L3MBTL1 | |
| SCHEMBL26324961 | 0.84 | L3MBTL1 (0.42) | TDP1L3MBTL1 | |
| SCHEMBL26324981 | 0.80 | MEN1 (0.38) | TSPOTDP1L3MBTL1 | |
| SCHEMBL20564573 | 0.80 | KDM4E (0.36) | KDM4ETDP1L3MBTL1 | |
| SCHEMBL26324909 | 0.77 | PPARG (0.31) | — | |
| SCHEMBL26324974 | 0.76 | PTGS1 (0.39) | TSPO | |
| SCHEMBL26324980 | 0.76 | PDCD1 (0.39) | TSPO | |
| SCHEMBL26325018 | 0.76 | ALDH1A1 (0.38) | KDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | TSPO 3646/4885KDM4E 1342/4885AR 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.