SCHEMBL26326734

SCHEMBL26326734

CCCCCCCC(O)c1c(F)cccc1F

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.41
SPHK1 Q9NYA1 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
GPR84 Q9NQS5 3/20 0.37
FFAR1 O14842 1/20 0.37
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
KCNH2 Q12809 1/20 0.36
PPARG P37231 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30606520 0.98 CSNK1E (0.39) CSNK1ESPHK1MEN1KMT2ASMN1; SMN2
SCHEMBL31287490 0.84 ALOX5 (0.44) PPARG
SCHEMBL21423075 0.83 MEN1 (0.41) CSNK1ESPHK1MEN1KMT2ASMN1; SMN2
SCHEMBL23564615 0.81 MEN1 (0.40) CSNK1ESPHK1MEN1KMT2ASMN1; SMN2
SCHEMBL20833289 0.81 CES2 (0.40) CES2CES1
SCHEMBL4290441 0.81 PPARG (0.42) CSNK1ESPHK1MEN1KMT2ASMN1; SMN2
SCHEMBL8746416 0.81 PPARG (0.42) CSNK1ESPHK1MEN1KMT2ASMN1; SMN2
SCHEMBL4825249 0.81 PPARG (0.42) CSNK1ESPHK1MEN1KMT2ASMN1; SMN2
SCHEMBL7523840 0.81 PPARG (0.42) CSNK1ESPHK1MEN1KMT2ASMN1; SMN2
SCHEMBL26326736 0.80 CSNK1E (0.42) CSNK1EPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE HPD, TALDO1, OGG1 CSNK1E 4154/4885SPHK1 3549/4885MEN1 1296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.