SCHEMBL26326973

SCHEMBL26326973

C1=Cc2oc3cccc(-c4cccc5oc6cccc(-c7nc(-c8ccccc8)nc(-c8ccc9c(ccc%10ccccc%109)c8)n7)c6c45)c3c2CC1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX15 P16050 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26292531 0.95 MAPT (0.33) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL25622508 0.93 MAPT (0.33) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL26034903 0.90 MAPT (0.34) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL26052121 0.89 ALDH1A1 (0.31) ALDH1A1MAPT
SCHEMBL24930643 0.88 L3MBTL1 (0.32) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL24930630 0.87 ALDH1A1 (0.34) ALDH1A1HPGDTSHRHSD17B10MAPK1
SCHEMBL24971098 0.86 KDM4E (0.32) KDM4EALDH1A1HSD17B10TP53SMN1; SMN2
SCHEMBL26375094 0.86 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL27391649 0.85 HSD17B1 (0.34)
SCHEMBL26080608 0.85 MMP12 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243102-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed