Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565362 | 0.88 | NR1H2 (0.35) | NR1H2NR1H3ALDH1A1GALK1SMN1; SMN2 | |
| SCHEMBL26327694 | 0.80 | TAS1R3 (0.40) | ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL26327702 | 0.77 | ESR1 (0.34) | LMNASMN1; SMN2ESR1CYP1A2GAA | |
| SCHEMBL26327742 | 0.77 | L3MBTL1 (0.38) | LMNAL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL26327699 | 0.75 | HDAC3 (0.33) | ALDH1A1ESR1 | |
| SCHEMBL26327677 | 0.74 | GAA (0.40) | ALDH1A1TSHRL3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL26327664 | 0.72 | LMNA (0.45) | ALDH1A1TSHRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL26327671 | 0.71 | MEN1 (0.38) | ALDH1A1TSHRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL26327713 | 0.68 | PPARG (0.41) | ALDH1A1LMNASMN1; SMN2CYP2C19KDM4E | |
| SCHEMBL20565012 | 0.67 | TAS1R3 (0.40) | ALDH1A1LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | NR1H2 3952/4885NR1H3 3551/4885ALDH1A1 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.