Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565056 | 0.83 | ALDH1A1 (0.33) | MEN1KMT2APKMALDH1A1PDE4B | |
| SCHEMBL26327758 | 0.80 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL26328011 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2TAS1R3 | |
| SCHEMBL26327751 | 0.79 | CHRM2 (0.43) | MEN1KMT2APKMALDH1A1TSHR | |
| SCHEMBL26327769 | 0.78 | CHRM2 (0.44) | MEN1KMT2APKMALDH1A1TSHR | |
| SCHEMBL26327651 | 0.73 | LMNA (0.44) | ALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL26328040 | 0.68 | ADH1A (0.38) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL26327648 | 0.67 | ADH1A (0.37) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL26327654 | 0.67 | TDP1 (0.40) | TDP1 | |
| SCHEMBL26328016 | 0.65 | HTT (0.35) | ALDH1A1TSHRHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | MEN1 296/4885KMT2A 127/4885PKM 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.