Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563496 | 0.90 | LMNA (0.69) | LMNACHRNB2CHRNA7CHRNA4PRPS1 | |
| SCHEMBL4678783 | 0.88 | LMNA (0.62) | LMNACHRNB2CHRNA7CHRNA4PRPS1 | |
| SCHEMBL9482398 | 0.86 | NPC1 (0.51) | LMNACHRNB2CHRNA7CHRNA4PRPS1 | |
| SCHEMBL3298831 | 0.85 | NPC1 (0.49) | LMNAPRPS1MEN1KMT2ANPC1 | |
| SCHEMBL9040262 | 0.82 | PRPS1 (0.52) | LMNACHRNB2CHRNA7CHRNA4PRPS1 | |
| SCHEMBL8875090 | 0.82 | PRPS1 (0.49) | LMNAPRPS1MEN1KMT2ANPC1 | |
| SCHEMBL8508894 | 0.81 | NPC1 (0.44) | LMNACHRNB2CHRNA4PRPS1MEN1 | |
| SCHEMBL5630090 | 0.81 | PRPS1 (0.43) | LMNACHRNB2CHRNA7CHRNA4PRPS1 | |
| SCHEMBL15779866 | 0.80 | LMNA (0.81) | LMNACHRNB2CHRNA7CHRNA4MEN1 | |
| SCHEMBL3303214 | 0.79 | NPC1 (0.51) | LMNACHRNB2CHRNA7CHRNA4PRPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016782-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |
| US-8163720-B2 | Pyrrolidinyl phenyl sulphonamides as modulators of ion channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110082117-A1 | PHENYL SULFONAMIDES AS MODULATORS OF ION CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-04-07 | — | — | US | disclosed |
| US-6143434-A | HIGH LUMINANCE AND A HIGH LUMINESCENT EFFICIENCY AT A LOW DRIVING VOLTAGE AND HAS EXCELLENT STABILITY IN REPETITIONS OF USE | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| US-4047964-A | BENZISOXAZOLE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-09-13 | — | — | US | disclosed |
| US-4040841-A | SENSITIZING DYE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |
| US-4018610-A | Supersensitized silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |
| US-4010037-A | Spectrally sensitized silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1977-03-01 | — | — | US | disclosed |
| US-3977883-A | Spectrally sensitized silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3967967-A | CYANINE DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-06 | — | — | US | disclosed |
| US-3966477-A | Spectrally sensitized silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082117-A1 | PHENYL SULFONAMIDES AS MODULATORS OF ION CHANNELS | TRPV1, KCNJ2, TRPA1 | LMNA 3348/4885CHRNB2 722/4885CHRNA7 652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.