Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6395431 | 0.92 | PRPS1 (0.49) | PRPS1MAPTHSD17B10LMNAMEN1 | |
| SCHEMBL11563496 | 0.86 | LMNA (0.69) | PRPS1MAPTHSD17B10LMNAMEN1 | |
| SCHEMBL4678783 | 0.85 | LMNA (0.62) | PRPS1MAPTHSD17B10LMNAMEN1 | |
| SCHEMBL2632811 | 0.82 | LMNA (0.54) | PRPS1MAPTHSD17B10LMNAMEN1 | |
| SCHEMBL8875090 | 0.82 | PRPS1 (0.49) | PRPS1MAPTHSD17B10LMNAMEN1 | |
| SCHEMBL9037446 | 0.81 | LMNA (0.76) | MAPTHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL9040247 | 0.79 | PRPS1 (0.54) | PRPS1MAPTHSD17B10LMNATP53 | |
| SCHEMBL9038637 | 0.79 | MAPT (0.57) | PRPS1MAPTHSD17B10LMNATP53 | |
| SCHEMBL5630090 | 0.78 | PRPS1 (0.43) | PRPS1MAPTHSD17B10LMNAMEN1 | |
| SCHEMBL3298831 | 0.78 | NPC1 (0.49) | PRPS1MAPTHSD17B10LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393574-B1 | Hexitol derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5053408-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0393574-A2 | Hexitol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |