Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744249 | 0.85 | NOTUM (0.74) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL10153796 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL7000350 | 0.82 | RAB9A (0.80) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL13515794 | 0.81 | NOTUM (0.66) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL13665153 | 0.80 | NOTUM (0.65) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL2949440 | 0.80 | HPGD (0.67) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL13665156 | 0.80 | NOTUM (0.65) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL1279945 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL7218028 | 0.79 | ALDH1A1 (0.76) | SMN1; SMN2GAAMAPK1RAB9ANPC1 | |
| SCHEMBL4910951 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAMAPK1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |