Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26334879 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL26349155 | 0.79 | LMNA (0.38) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL26334712 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1582980 | 0.78 | GABRA5 (0.52) | ALDH1A1MAPTGABRA5GABRB2HSD17B10 | |
| SCHEMBL26339399 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL26337222 | 0.77 | HTR2B (0.36) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL26337113 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL28049431 | 0.77 | GABRA5 (0.50) | ALDH1A1MAPTGABRA5GABRB2HSD17B10 | |
| SCHEMBL9203531 | 0.77 | HSD17B10 (0.38) | ALDH1A1MAPTSMN1; SMN2GABRA5GABRB2 | |
| SCHEMBL11415710 | 0.76 | L3MBTL1 (0.59) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |