Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775913 | 0.73 | HSD17B3 (0.58) | CLK2GAAMGAMSIMGAM2 | |
| SCHEMBL26348265 | 0.72 | MAOA (0.52) | GAAALDH1A1KDM4ESMN1; SMN2CASP7 | |
| SCHEMBL3779672 | 0.70 | PGAM1 (0.58) | CLK2GAAMGAMSIMGAM2 | |
| SCHEMBL3782322 | 0.66 | CLK2 (0.63) | CLK2GAAMGAMSIMGAM2 | |
| SCHEMBL14172327 | 0.64 | GAA (0.49) | CLK2GAAMGAMSIMGAM2 | |
| SCHEMBL14169827 | 0.63 | CLK2 (0.48) | CLK2GAAMGAMSIMGAM2 | |
| SCHEMBL8745801 | 0.63 | KDM4E (0.64) | CLK2GAAMGAMSIMGAM2 | |
| SCHEMBL17949776 | 0.62 | RXRA (0.72) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5240410 | 0.62 | GAA (0.56) | GAAALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL9838561 | 0.61 | MGAM (1.00) | CLK2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |