Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NQO1 | P15559 | 2/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26339996 | 0.84 | MAOA (0.53) | MAOAMAOBHSD17B10KDM4EMEN1 | |
| SCHEMBL26335692 | 0.84 | CA12 (0.48) | HSD17B10KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26350176 | 0.81 | MAOA (0.50) | MAOAMAOBHSD17B10KDM4EMEN1 | |
| SCHEMBL30753455 | 0.80 | CYP2C19 (0.54) | MAOAMAOBKDM4EMEN1KMT2A | |
| SCHEMBL26340317 | 0.72 | KDM4E (0.69) | HSD17B10KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26338486 | 0.72 | CLK2 (0.43) | MAOAMAOBHSD17B10KDM4EMEN1 | |
| SCHEMBL26339798 | 0.71 | MAOA (0.58) | MAOAMAOBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2540914 | 0.69 | ALDH1A1 (0.53) | MAOAHSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL27752820 | 0.69 | HSD17B3 (0.60) | MAOAMAOBHSD17B10KDM4EKMT2A | |
| SCHEMBL27752675 | 0.69 | KDM4E (0.62) | KDM4EMEN1KMT2ASMN1; SMN2NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |