Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | PPIG | Q13427 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26340042 | 0.85 | ALDH1A1 (0.42) | KDM4EALDH1A1POLBALOX15RXFP1 | |
| SCHEMBL23352415 | 0.84 | MAPT (0.45) | KDM4EALDH1A1POLBBCHERAB9A | |
| SCHEMBL19403922 | 0.84 | MAPT (0.45) | KDM4EALDH1A1POLBBCHERAB9A | |
| SCHEMBL25771258 | 0.74 | TP53 (0.39) | KDM4EALDH1A1ALOX15 | |
| SCHEMBL25569236 | 0.73 | ALDH1A1 (0.35) | KDM4EALDH1A1POLBPPIDPPIG | |
| SCHEMBL26340378 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1GAAHPGDNPC1 | |
| SCHEMBL26340737 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBGAAHPGD | |
| SCHEMBL14866651 | 0.70 | TP53 (0.41) | ALDH1A1POLBALOX15GAAL3MBTL1 | |
| SCHEMBL23471602 | 0.70 | TP53 (0.41) | ALDH1A1POLBALOX15GAAL3MBTL1 | |
| SCHEMBL20993884 | 0.70 | TP53 (0.41) | ALDH1A1POLBALOX15GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303481-A1 | LONG-ACTING LOW-ADDICTION HNK DERIVATIVE AND PREPARATION METHOD THEREFOR | SHENZHEN RUIJIAN BIOTECHNOLOGY CO., LTD (CN) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303481-A1 | LONG-ACTING LOW-ADDICTION HNK DERIVATIVE AND PREPARATION METHOD THEREFOR | OPRK1, OPRL1, NTRK1 | KDM4E 3375/4885ALDH1A1 3380/4885POLB 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.