Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899854 | 0.95 | TSHR (0.53) | TSHRALDH1A1HSD17B10TRPA1CDC25B | |
| SCHEMBL447793 | 0.94 | TSHR (0.51) | TSHRALDH1A1HSD17B10TRPA1CDC25B | |
| Calcium SCHEMBL8504089 | 0.94 | TSHR (0.51) | TSHRALDH1A1HSD17B10TRPA1CDC25B | |
| Lithium SCHEMBL11047758 | 0.94 | TSHR (0.51) | TSHRALDH1A1HSD17B10TRPA1CDC25B | |
| SCHEMBL9244736 | 0.94 | TSHR (0.51) | TSHRALDH1A1HSD17B10TRPA1CDC25B | |
| Potassium SCHEMBL41206 | 0.94 | TSHR (0.51) | TSHRALDH1A1HSD17B10TRPA1CDC25B | |
| SCHEMBL1175633 | 0.94 | TSHR (0.51) | TSHRALDH1A1HSD17B10TRPA1CDC25B | |
| SCHEMBL16414281 | 0.94 | TSHR (0.51) | TSHRALDH1A1HSD17B10TRPA1CDC25B | |
| SCHEMBL664364 | 0.85 | ALDH1A1 (0.55) | TSHRALDH1A1HSD17B10TRPA1KDM4E | |
| Potassium SCHEMBL5865052 | 0.84 | ALDH1A1 (0.54) | TSHRALDH1A1HSD17B10TRPA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443482-B1 | BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | claimed |
| US-20100315588-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | claimed |
| US-20260147141-A1 | SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES | BAUSCH + LOMB IRELAND LIMITED (IE) | 2026-05-28 | — | — | US | disclosed |
| US-20260078209-A1 | SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES | BAUSCH & LOMB IRELAND LTD (IE) | 2026-03-19 | — | — | US | disclosed |
| EP-4646240-A1 | BIOMEDICAL DEVICES HAVING A SURFACE COATING | Bausch + Lomb Ireland Limited (IE) | 2025-11-12 | — | — | EP | disclosed |
| US-20250321364-A1 | SURFACE MODIFIED OPHTHALMIC DEVICES | BAUSCH & LOMB IRELAND LTD (IE) | 2025-10-16 | — | — | US | disclosed |
| US-20240240047-A1 | BIOMEDICAL DEVICES HAVING A SURFACE COATING | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2024-07-18 | — | — | US | disclosed |
| WO-2024146878-A1 | BIOMEDICAL DEVICES HAVING A SURFACE COATING | BAUSCH + LOMB IRELAND LIMITED (IE) | 2024-07-11 | — | — | WO | disclosed |
| EP-3834018-A1 | OPHTHALMIC DEVICES | Bausch & Lomb Incorporated (US) | 2021-06-16 | — | — | EP | disclosed |
| CN-112930487-A | Ophthalmic device | 鲍希与洛姆伯股份有限公司 | 2021-06-08 | — | — | CN | disclosed |
| US-10668676-B2 | Ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2020-06-02 | — | — | US | disclosed |
| EP-2443485-A2 | BIOMEDICAL DEVICES | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| US-8133960-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-8083348-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2011-12-27 | — | — | US | disclosed |
| WO-2010147875-A2 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010147864-A2 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010147876-A2 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20100317816-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317817-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100315588-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078209-A1 | SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES | CRYAA, CRYAB, CRYZ | TSHR 553/4885ALDH1A1 2751/4885HSD17B10 1846/4885 |
| US-20260147141-A1 | SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES | EPCAM, STIM1, SMCHD1 | TSHR 1380/4885ALDH1A1 2187/4885HSD17B10 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.