Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 3/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26344046 | 0.84 | DUT (0.43) | ACACBS1PR3PDE2AIDH1DUT | |
| SCHEMBL29589397 | 0.84 | ACACB (0.41) | ACACBS1PR3IDH1DUTPDE9A | |
| SCHEMBL26344040 | 0.84 | ACACB (0.41) | ACACBS1PR3IDH1DUTPDE9A | |
| SCHEMBL26344032 | 0.84 | ACACB (0.41) | ACACBS1PR3IDH1DUTPDE9A | |
| SCHEMBL26344024 | 0.84 | ACACB (0.41) | ACACBS1PR3IDH1DUTPDE9A | |
| SCHEMBL29589354 | 0.84 | ACACB (0.41) | ACACBS1PR3IDH1DUTPDE9A | |
| SCHEMBL26344022 | 0.82 | PDE9A (0.46) | PDE2APDE9A | |
| SCHEMBL26345271 | 0.78 | CASR (0.36) | PDE2APDE9AP2RX3 | |
| SCHEMBL26344050 | 0.77 | IDH1 (0.52) | ACACBIDH1DUTSOS1 | |
| SCHEMBL26344164 | 0.77 | MEN1 (0.39) | PDE2APDE9AP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |