Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE6C | P51160 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26344164 | 0.86 | MEN1 (0.39) | PDE9AMEN1PKMGFERKMT2A | |
| SCHEMBL26344898 | 0.85 | MTOR (0.38) | PDE9AMEN1PKMGFERKMT2A | |
| SCHEMBL26344153 | 0.85 | P2RX3 (0.39) | PDE9A | |
| SCHEMBL26344029 | 0.82 | ACACB (0.39) | PDE9APDE2A | |
| SCHEMBL26345271 | 0.81 | CASR (0.36) | PDE9APDE2ACASR | |
| SCHEMBL26345510 | 0.73 | PDE9A (0.34) | PDE9A | |
| SCHEMBL26345338 | 0.69 | PDE9A (0.40) | PDE9AFABP4PDE2ALMNA | |
| SCHEMBL26345453 | 0.68 | PDE2A (0.43) | PDE9APDE2ALMNA | |
| SCHEMBL26344131 | 0.67 | PDE2A (0.45) | PDE9APKMPDE2ALMNA | |
| SCHEMBL11616050 | 0.67 | ALDH1A1 (0.41) | PKMLMNAGAACASRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |