Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26344898 | 0.88 | MTOR (0.38) | MEN1KMT2APKMPDE9AKDM4E | |
| SCHEMBL26344022 | 0.86 | PDE9A (0.46) | MEN1KMT2APKMPDE9AFABP4 | |
| SCHEMBL26345271 | 0.84 | CASR (0.36) | PDE9AKDM4EPGRPDE2AP2RX3 | |
| SCHEMBL26344153 | 0.83 | P2RX3 (0.39) | PDE9AKDM4EP2RX3 | |
| SCHEMBL26344167 | 0.78 | PGR (0.37) | PDE9APGRPDE2ANR1I2EGFR | |
| SCHEMBL30459378 | 0.78 | PGR (0.37) | PDE9APGRPDE2ANR1I2EGFR | |
| SCHEMBL26344212 | 0.78 | PDE9A (0.43) | PDE9APGRPDE2AALDH1A1HSD17B10 | |
| SCHEMBL26344029 | 0.77 | ACACB (0.39) | PDE9APDE2AP2RX3 | |
| SCHEMBL26345510 | 0.76 | PDE9A (0.34) | PDE9AP2RX3 | |
| SCHEMBL26345985 | 0.76 | PDE2A (0.48) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |