Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 6/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459380 | 1.00 | IDH1 (0.34) | IDH1P2RX3P2RX7XDH | |
| SCHEMBL31207897 | 1.00 | IDH1 (0.34) | IDH1P2RX3P2RX7XDH | |
| SCHEMBL31364128 | 0.82 | OGA (0.39) | IDH1 | |
| SCHEMBL26344128 | 0.82 | OGA (0.39) | IDH1 | |
| SCHEMBL26345510 | 0.81 | PDE9A (0.34) | P2RX3P2RX7 | |
| SCHEMBL24469635 | 0.80 | XDH (0.32) | IDH1XDH | |
| SCHEMBL30599760 | 0.80 | XDH (0.32) | IDH1XDH | |
| SCHEMBL30459378 | 0.76 | PGR (0.37) | IDH1P2RX3 | |
| SCHEMBL26344167 | 0.76 | PGR (0.37) | IDH1P2RX3 | |
| SCHEMBL26344101 | 0.73 | SCN1A (0.39) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |