Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26344125 | 0.82 | PDE9A (0.45) | PDE9AP2RX3 | |
| SCHEMBL31207897 | 0.81 | IDH1 (0.34) | P2RX3P2RX7 | |
| SCHEMBL26344146 | 0.81 | IDH1 (0.34) | P2RX3P2RX7 | |
| SCHEMBL30459380 | 0.81 | IDH1 (0.34) | P2RX3P2RX7 | |
| SCHEMBL26344164 | 0.76 | MEN1 (0.39) | PDE9AP2RX3 | |
| SCHEMBL26344898 | 0.75 | MTOR (0.38) | PDE9AP2RX3 | |
| SCHEMBL26345271 | 0.74 | CASR (0.36) | PDE9AP2RX3 | |
| SCHEMBL26344022 | 0.73 | PDE9A (0.46) | PDE9A | |
| SCHEMBL31364128 | 0.73 | OGA (0.39) | PDE9A | |
| SCHEMBL26344128 | 0.73 | OGA (0.39) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |