Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766728 | 0.76 | OPRL1 (0.52) | OPRM1OPRL1 | |
| SCHEMBL19153839 | 0.76 | OPRM1 (0.49) | OPRM1OPRL1 | |
| SCHEMBL22538493 | 0.74 | OPRM1 (0.54) | OPRM1OPRL1 | |
| SCHEMBL19153406 | 0.73 | OPRM1 (0.53) | OPRM1OPRL1 | |
| SCHEMBL22540296 | 0.71 | OPRL1 (0.52) | OPRM1OPRL1 | |
| SCHEMBL22540261 | 0.71 | OPRM1 (0.46) | OPRM1OPRL1 | |
| SCHEMBL19145225 | 0.70 | OPRM1 (0.53) | OPRM1OPRL1 | |
| SCHEMBL19105816 | 0.69 | OPRL1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19095149 | 0.69 | OPRL1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19095146 | 0.69 | OPRL1 (1.00) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303573-A1 | 3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | Grünenthal GmbH (DE) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303573-A1 | 3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | OPRK1, OPRD1, OPRL1 | OPRM1 5/4885OPRL1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.