SCHEMBL26348102

SCHEMBL26348102

CC(O)(C(=O)O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.54
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
PDK1 Q15118 3/20 0.34
PDK2 Q15119 3/20 0.34
PDK3 Q15120 3/20 0.34
PDK4 Q16654 3/20 0.34
CA2 P00918 2/20 0.32
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
LMNA P02545 1/20 0.32
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26348105 0.90 THRB (0.46) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL569205 0.81 ALDH1A1 (0.53) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL568925 0.81 ALDH1A1 (0.53) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL568924 0.81 ALDH1A1 (0.53) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL497440 0.77 THRB (0.56) THRBALDH1A1TSHRCA2CA1
SCHEMBL1790510 0.77 THRB (0.56) THRBALDH1A1TSHRCA2CA1
SCHEMBL28925386 0.77 THRB (0.56) THRBALDH1A1TSHRCA2CA1
SCHEMBL5336890 0.77 THRB (0.56) THRBALDH1A1TSHRCA2CA1
SCHEMBL5337470 0.77 THRB (0.56) THRBALDH1A1TSHRCA2CA1
Acetic Acid SCHEMBL28332245 0.75 THRB (0.60) THRBALDH1A1TSHRCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230305398-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed